@santiago
I've been using this machine running Mac OS X with Painter 10 and Intuos 2 and unless you're using some really complex brushes it's very responsive. I was never doing this professionally, but for scratching the occasional artistic expression itch it's perfect. I don't think I've ever used it with display resolutions higher than 1280x1024 though, I'm not even sure it can drive bigger displays TBH, it can probably do 1920x1200 🤔, but not higher.